hig.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard-cite-them-right
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • sv-SE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • de-DE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Not getting used to the smell – Chemical intolerance as lack of habituation
Högskolan i Gävle, Akademin för hälsa och arbetsliv, Avdelningen för arbets- och folkhälsovetenskap, Arbetshälsovetenskap. Högskolan i Gävle, Centrum för belastningsskadeforskning. Department of Psychology, Umeå University, Umeå, Sweden.ORCID-id: 0000-0003-4088-0025
Department of Psychology, Umeå University, Umeå, Sweden.
2017 (Engelska)Ingår i: Biological Psychology, ISSN 0301-0511, E-ISSN 1873-6246, Vol. 129, nr Suppl. C, s. 377-Artikel i tidskrift, Meeting abstract (Refereegranskat) Published
Abstract [en]

Background:

Chemical intolerance is a prevalent, medically unexplained symptom characterized by diverse symptoms following weak chemical exposure. The symptom-eliciting exposures are often odorous, and include perfume, fabric softeners and fragrant flowers. Several explanatory mechanisms have been proposed, but empirical data is scarce. By reanalyzing data from previous studies, we aimed to find a criterion for chemical intolerance based on reactions to actual chemical exposure.

Method:

We grouped participants from six previous studies based on their pattern of habituation to weak olfactory (amylacetate and n-butanol) and trigeminal (CO2 and acrolein) compounds. In two studies utilizing event-related potentials, and one functional magnetic resonance imaging study, stimuli were presented intranasally using a dynamic olfactometer. An exposure chamber that allowed full body exposure was used in the remaining three studies.

Results:

Individuals who did not habituate to weak chemical exposure, compared with those who did, reported (1) increasing symptoms during the course of the exposure, (2) greater problems with odors in everyday life, and (3) greater levels of everyday distress. They (4) performed worse on cognitively demanding tasks during exposure, and differed in measures of (5) the autonomic nervoussystem(respiratoryrateandpulseratevariability),(6)low-level inflammation and oxidative stress, and (7) the so called pain matrix of the brain.

Discussion:

Lack of habituation to weak chemical exposure may be a fruitful method of defining a sub-group of chemical intolerance.

Ort, förlag, år, upplaga, sidor
2017. Vol. 129, nr Suppl. C, s. 377-
Nationell ämneskategori
Arbetsmedicin och miljömedicin
Identifikatorer
URN: urn:nbn:se:hig:diva-25598DOI: 10.1016/j.biopsycho.2017.08.025ISI: 000416436800055OAI: oai:DiVA.org:hig-25598DiVA, id: diva2:1160204
Tillgänglig från: 2017-11-24 Skapad: 2017-11-24 Senast uppdaterad: 2018-03-13Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltext

Personposter BETA

Andersson, Linus

Sök vidare i DiVA

Av författaren/redaktören
Andersson, Linus
Av organisationen
ArbetshälsovetenskapCentrum för belastningsskadeforskning
I samma tidskrift
Biological Psychology
Arbetsmedicin och miljömedicin

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 74 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard-cite-them-right
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • sv-SE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • de-DE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf