Household food insecurity is defined as inadequate or insecure access to food because of financial constraints. The objective of this short article is to highlight the prevalence and determinants of food insecurity in Mozambique during the past three years. Food insecurity is an important societal and public health problem in Mozambique, and its main determinants are climate change, transportation, and poverty. There is a urgent need for research that can provide a deeper understanding of the determinants of food insecurity in the country and disentangle potential relationships with physical and psychological health outcomes.