According to Vening Meinesz-Moritz (VMM) global inverse isostatic problem, either the Moho density contrast (crust-mantle density contrast) or the Moho geometry can be estimated by solving a non-linear Fredholm integral equation of the first kind. Here solutions to the two Moho parameters are presented by combining the global geopotential model (GOCO-03S), topography (DTM2006) and a seismic crust model, the latter being the recent digital global crustal model (CRUST1.0) with a resolution of 1A(0)x1A(0). The numerical results show that the estimated Moho density contrast varies from 21 to 637 kg/m(3), with a global average of 321 kg/m(3), and the estimated Moho depth varies from 6 to 86 km with a global average of 24 km. Comparing the Moho density contrasts estimated using our leastsquares method and those derived by the CRUST1.0, CRUST2.0, and PREM models shows that our estimate agrees fairly well with CRUST1.0 model and rather poor with other models. The estimated Moho depths by our least-squares method and the CRUST1.0 model agree to 4.8 km in RMS and with the GEMMA1.0 based model to 6.3 km.