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Associations between lower urinary tract dysfunction and health-related quality of life in children with chronic kidney disease
Division of Pediatrics, Department of Clinical Science, Technology and Intervention, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Department of Neurobiology, Care Sciences and Society, Division of Nursing, Karolinska Institutet, Stockholm, Sweden.
Division of Pediatrics, Department of Clinical Science, Technology and Intervention, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Högskolan i Gävle, Akademin för hälsa och arbetsliv, Avdelningen för socialt arbete och psykologi, Socialt arbete. Department of Neurobiology, Care Sciences and Society, Division of Social Work, Karolinska Institutet, Stockholm, Sweden.
2016 (engelsk)Inngår i: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 105, nr 8, s. 959-966Artikkel i tidsskrift (Fagfellevurdert) Published
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Abstract [en]

Aim Little is known about the health-related quality of life (HRQoL) of children with lower urinary tract dysfunction (LUTD) and chronic kidney disease (CKD). We investigated LUTD and other possible predictors of impaired HRQoL in children with conservatively treated moderate to severe CKD or with a kidney transplant.

Methods All 64 children with CKD or a kidney transplant treated at Karolinska University Hospital, Stockholm, Sweden, between June 2011 and December 2012 were approached and 59 children aged 8-18 were enrolled in the study. Lower urinary tract function was evaluated with voiding history, frequency and volume chart, uroflowmetry and post void ultrasound measurements. Self-reported HRQoL was assessed with validated generic instruments.

Results The HRQoL of the study cohort was as good as the general paediatric population, apart from the physical and psychological well-being dimensions, and was no different to children with other chronic conditions. Urinary incontinence, but not LUTD in general, was associated with impaired HRQoL, as was having a kidney transplant and being female in some dimensions.

Conclusion LUTD was common in children with CKD or a kidney transplant but did not affect their general HRQoL. Predictors of impaired HRQoL included incontinence, having had a kidney transplant and being female.

sted, utgiver, år, opplag, sider
2016. Vol. 105, nr 8, s. 959-966
Emneord [en]
Bladder dysfunction, Chronic kidney disease, Health-related quality of life, Kidney transplant, Lower urinary tract symptoms
HSV kategori
Identifikatorer
URN: urn:nbn:se:hig:diva-21502DOI: 10.1111/apa.13453ISI: 000382741100031PubMedID: 27127995Scopus ID: 2-s2.0-84971351015OAI: oai:DiVA.org:hig-21502DiVA, id: diva2:929040
Merknad

Funding:

Freemasons in Stockholm Foundation for Children's Welfare  

Samaritan Foundation  

Clas Groschinskys Memorial Fund  

Sven Jerring Foundation  

Department of Clinical Science, Intervention and Technology (CLINTEC)  

Karolinska Institutet  

Stockholm County Council 

Tilgjengelig fra: 2016-05-17 Laget: 2016-05-17 Sist oppdatert: 2018-03-13bibliografisk kontrollert

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