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Ethnic Differences in the Risk Factors and Severity of Coronary Artery Disease: a Patient-Based Study in Iran
Department of Health Sciences, Section of Public Health Sciences, Mid Sweden University, Sundsvall, Sweden; Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID iD: 0000-0002-1068-8860
Department of Psychology, Mid Sweden University, Östersund, Sweden.
Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Health Sciences, Section of Public Health Sciences, Mid Sweden University, Sundsvall, Sweden.
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2017 (English)In: Journal of Racial and Ethnic Health Disparities, ISSN 2197-3792Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background

Diverse ethnic groups may differ regarding the risk factors and severity of coronary artery disease (CAD). This study sought to assess the association between ethnicity and CAD risk and severity in six major Iranian ethnic groups.

Methods

In this study, 20,165 documented coronary artery disease patients who underwent coronary angiography at a tertiary referral heart center were recruited. The demographic, laboratory, clinical, and risk factor data of all the patients were retrieved. The Gensini score (an indicator of CAD severity) was calculated for all, and the risk factors and severity of CAD were compared between the ethnical groups, using adjusted standardized residuals, Kruskal–Wallis test, and multivariable regression analysis.

Results

The mean age of the participants (14,131 [70.1%] men and 6034 [29.9%] women) was 60.7 ± 10.8 years. The Fars (8.7%) and Gilak (8.6%) ethnic groups had the highest prevalence of ≥4 simultaneous risk factors. The mean Gensini score was the highest for the Gilaks (77.1 ± 55.9) and the lowest among the Lors (67.5 ± 52.8). The multivariable regression analysis showed that the Gilaks had the worst severity (β 0.056, 95% CI 0.009 to 0.102; P = 0.018), followed by the Torks (β 0.032, 95% CI 0.005 to 0.059; P = 0.020). Meanwhile, the Lors showed the lowest severity (β −0.087, 95% CI −0.146 to −0.027; P = 0.004).

Conclusions

This study found that there was heterogeneity in CAD severity and a diverse distribution in its well-known traditional risk factors among major Iranian ethnic groups.

Place, publisher, year, edition, pages
2017.
Keyword [en]
Health status disparities, Ethnicity, Coronary artery disease, Iran
National Category
Health Sciences
Identifiers
URN: urn:nbn:se:hig:diva-24816DOI: 10.1007/s40615-017-0408-3PubMedID: 28776137Scopus ID: 2-s2.0-85026809542OAI: oai:DiVA.org:hig-24816DiVA: diva2:1130730
Available from: 2017-08-10 Created: 2017-08-10 Last updated: 2017-08-18Bibliographically approved

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CiteExportLink to record
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