This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary objective of this review is to compare the potential harms of treatment for spinal metastatic disease for the following treatments: 1. Surgical intervention. 2. Surgical intervention with radiation therapy. 3. Radiation therapy alone. Our secondary objectives are: 1. comparing the harms of different surgical methods; 2. comparing the harms between different radiation protocols.