A crucial question concerning interfacial wetting phenomena, is how an organic solvent interacts with a tenside layer's hydrocarbon chains. This interaction will, as an example, influence the swelling of the tenside layer and, hence, the curvature of inverted w/o micelles. We have chosen to use chromatographic measurements to study the interactions between solvents and tensides. From HPLC, the retention time will be a measure on the solubility of the solvent in the hydrocarbon chain layer. From measurements of the temperature dependence and analyzing both the shift in retention time and peak tailing, an adsorption isotherm can be calculated. The concentration dependence, on the other hand, yield information on differences in solubility at different saturation levels. Combining the experimental results with thermodynamic modeling opens for a molecular understanding of solvent-tenside interactions.