hig.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard-cite-them-right
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • sv-SE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • de-DE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Immunohistochemical localization of alpha(1a)-adrenoreceptors in muscle spindles of rabbit masseter muscle
Department of Veterinary Morphophysiology and Animal Productions, University of Bologna, Ozzano dell'Emilia, Italy.
Department of Veterinary Morphophysiology and Animal Productions, University of Bologna, Ozzano dell'Emilia, Italy.
Department of Veterinary Morphophysiology and Animal Productions, University of Bologna, Ozzano dell'Emilia, Italy.
Department of Veterinary Morphophysiology and Animal Productions, University of Bologna, Ozzano dell'Emilia, Italy.
Show others and affiliations
2006 (English)In: Tissue & Cell, ISSN 0040-8166, E-ISSN 1532-3072, Vol. 38, no 2, 121-125 p.Article in journal (Refereed) Published
Abstract [en]

The expression of alpha(1a)-adrenoreceptors (alpha(1a)-ARs) within the muscle spindles of rabbit masseter muscle was investigated. The alpha(1a)-ARs were detected by immunohistochemical fluorescent method and examined along the entire length of 109 cross serially sectioned spindles. The sympathetic fibers were visualized by the immunofluorescent labeling of the noradrenaline synthesizing enzymes tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). In order to recognize the intrafusal muscle fiber types, antibodies for different myosin heavy chain isoforms (MyHCI) were used. TH and DBH immunolabeled nerve fibers have been observed within the capsule lamellar layers, in the periaxial fluid space and close to intrafusal muscle fibers. The alpha(1a)-ARs were detected on the smooth muscle cells of the blood vessels coursing in the muscle and in the capsule lamellar layers or within the periaxial fluid space of the spindles. Moreover, at the polar regions of a high percentage (88.1%) of muscle spindles a strong alpha(1a)-ARs immunoreactivity was present on the intrafusal muscle fibers. In double immunostained sections for alpha(1a)-ARs and MyHCI it was evidenced that both bag, and nuclear chain fibers express alpha(1a)-ARs. The receptors that we have detected by immunofluorescence may support a direct control by adrenergic fibers on muscle spindle.

Place, publisher, year, edition, pages
2006. Vol. 38, no 2, 121-125 p.
Keyword [en]
Animals, Immunohistochemistry methods, Male, Masseter, Muscle cytology metabolism ultrastructure, Muscle Fibers cytology metabolism, Muscle Spindles cytology metabolism ultrastructure, Neurotransmitter, Agents metabolism, Norepinephrine metabolism, Rabbits, Receptors, Adrenergic alpha-1 immunology metabolism
National Category
Environmental Health and Occupational Health
Identifiers
URN: urn:nbn:se:hig:diva-2802DOI: 10.1016/j.tice.2005.12.003ISI: 000237095000005PubMedID: 16510160Scopus ID: 2-s2.0-33645155392OAI: oai:DiVA.org:hig-2802DiVA: diva2:119464
Available from: 2007-11-21 Created: 2007-11-21 Last updated: 2016-10-31Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Johansson, Håkan
By organisation
Centre for Musculoskeletal Research
In the same journal
Tissue & Cell
Environmental Health and Occupational Health

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 44 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard-cite-them-right
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • sv-SE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • de-DE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf