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Quality of life following allogeneic stem cell transplantation, comparing parents' and children's perspective
Department of Paediatrics, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID iD: 0000-0001-8448-7917
Department of Paediatrics, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Department of Paediatrics, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
2006 (English)In: Pediatric Transplantation, ISSN 1397-3142, E-ISSN 1399-3046, Vol. 10, no 4, p. 491-496Article in journal (Refereed) Published
Abstract [en]

There is insufficient knowledge about the quality of life (QoL) among children after allogeneic stem cell transplantation (SCT). We recently reported an overall, good self-assessed QoL and health in 52 children who were three yr or more beyond SCT. The focus of this paper is the QoL as assessed by their parents, of whom 42 participated in the study. Using Swedish child health questionnaire (SCHQ)-PF50, parents rated their children's QoL lower on both the psychosocial (p<0.001) and physical summary scales (p<0.001) than the normative group of parents of children without chronic disease. Although essentially following each other, parent scores tended to be lower than children's own SCHQ-CF87 scores, particularly in the domains 'role socially due to physical limitations' (p<0.01) and 'self-esteem' (p<0.05). In the 'bodily pain' domain, patients' and parents' low scores agreed. The child's condition had a greater impact on parents' emotional situation than in the norm population (p<0.001). The severity of the child's physician-rated late effects (p<0.05) or of self-assessed subjective symptoms (p<0.01-0.05) was associated with a lower parental rating of the child's QoL. High Lansky or Karnofsky scores corresponded, respectively, to higher psychosocial (p<0.05) and physical (p<0.05) summary scores. It is concluded that as children, parents, and clinicians do not necessarily adopt similar views of a child's illness and of its impact on the child's life, clarity with regard to who is responsible for assessing the child's QoL is crucial when interpreting pediatric QoL studies.

Place, publisher, year, edition, pages
2006. Vol. 10, no 4, p. 491-496
Keywords [en]
allogeneic, children, health, parents, stem cell transplantation, quality of life
National Category
Other Medical Sciences
Identifiers
URN: urn:nbn:se:hig:diva-28709DOI: 10.1111/j.1399-3046.2006.00507.xISI: 000237635300016PubMedID: 16712609Scopus ID: 2-s2.0-33646873456OAI: oai:DiVA.org:hig-28709DiVA, id: diva2:1266893
Available from: 2018-11-29 Created: 2018-11-29 Last updated: 2020-12-16Bibliographically approved

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Forinder, Ulla

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