Production, management, use, and end-of-life of buildings has a large impact on climate change. Therefore, environmental targets are set to lower the greenhouse gas (GHG) emissions from the building sector. To reach these targets building regulation and voluntary environmental assessment methods (EAMs) that evaluate and certify the building's environmental impact are put forward as tools to push the building sector towards lower GHG emissions. In Sweden, building design is governed by building regulations and the dominant EAM is ‘Miljöbyggnad’ (MB) (“Environmental building”). Today, more than 1900 buildings have been certified by MB and it has influenced the building and property sector. In this chapter the potential impact MB and the linked Swedish building regulations have on building performance, energy use and GHG emissions, will be reviewed and discussed. The analysis investigates several of the MB’s indicators, evaluate to what degree EAMs can influence the design of the building and the energy system to lower the energy use and GHG emissions based on material choices. The analysis presents important aspects that may influence the design of the building and its energy system and what challenges and possibilities the indicators, criteria and regulations can have on buildings and climate change. In addition, some modification and suggestion for improvements are presented.