This research study is about the evaluation of mechanical properties of locally prepared Cored 6” self-interlocking blocks. Currently, all the construction practices, whether brick masonry, block masonry, or reinforced concrete, are time consuming, relatively energy inefficient, not eco-friendly, and non-sustainable. Another issue in masonry construction is that the strength and behavior of bricks or blocks masonry depend upon the properties of the binding material (mortar) used in masonry wall joints. Considering these issues, Eco Blocks are newly introduced interlocking blocks with different sizes and shapes. Construction with interlocking blocks is faster, economical, and easier, as they do not require binding material. The aim of this study was to obtain the mechanical properties such as the compressive strength (individual block and prism), diagonal tensile strength, shear parameters, modulus of elasticity, shear modulus, and flexural strength of Cored 6′′ Eco Blocks through comprehensive experimental investigation. These showed encouraging results as compared with typical interlocking compressed earth blocks and also satisfied the threshold set forth by the international standards regulating earth construction. The compressive and flexural strengths of the blocks have been obtained as 6.03 MPa and 1.66 MPa, respectively. Based on the results outcomes, Cored 6” Eco Blocks can be utilized in load bearing walls.