A Chinese proverb observes that women “hold up half the sky”, yet often in science education we have ignored the knowledge generated by feminist researchers about how females engage and participate in science. Further, science education has often failed to consider the implications from feminist critiques of science on science education. This chapter will provide a feminist perspective on who generates knowledge in science education and what knowledge is acceptable as ‘scientific’ by the field. Second, we will discuss the culture of science education and discuss whether science educators value the knowledge produced by gender and feminist researchers. In particular, we will examine the integration (or lack thereof) of gender issues into the dominant areas in science education research, such as teachers’ pedagogical content knowledge, the development of students’ science knowledge through inquiry, the role of conceptual change, and teachers’ preparation and professional development programs. Third, we will provide examples of how gender theory and feminist perspectives in science education could generate new knowledge about gender and science education.