The purpose of this study was to investigate the association between physical activity and perceived stress, energy and musculoskeletal disorders among office-workers and warehouse-workers and also to see if there were any differences depending on work-place and gender. The method that was used to collect data was three different validated questionnaires that measured stress and energy (the Stress-Energy questionnaire), musculoskeletal disorders (intensity and localization of pain, a Pain Drawing questionnaire with a VAS-scale) and physical activity (IPAQ – the short version). Eighty-eight workers participated in the study. Forty-seven of them were office-workers and forty-one were warehouse-workers. The result showed that there was a positive association between the variables stress and musculoskeletal disorders (r=,339) (p=,003) and also stress and energy (r=,228) (p=,033) among all workers. The warehouse-workers perceived more muscle-pain (p=,032) and less energy (p=,069) than the office-workers. Among the office-workers were the men more physically active then the women (p=,002). There was also a tendency that the more physically active the office-workers were, the less stressed they felt (-r=,294) (p=,059). The conclusions are that physical activity seems to be associated with a lower stress-level among the office-workers and that the association between stress and pain could be different depending on psychical activity at work.