This thesis deals with patients in a rural area of southern Africa and poses these basic questions: What does it mean to be ill in this part of the world and what do patients' life-worlds look like? In order to find answers to these questions, an in-depth fieldwork was carried out through which I was able to study how patients reacted to illness. I followed twenty patients in their search of ease, of which ten were members of Chief Mataga's family, with whom I was staying. Each patient, some relative(s) and the traditional healer(s) and faith healer(s) consulted constituted a "multi-episodical" case. In addition, a questionnaire was applied in order to collect supplementary information. A further area of research was the various factors which negatively and positively influenced the lives of people in the area. I examined those factors from both the insider and an outsider perspective and concluded that the phenomenon of illness and healing need to be regarded holistically and that it is of crucial importance to acknowledge patients' own ideas concerning those issues.