Four young adults diagnosed with Asperger's syndrome were interviewed to learn more about what impact this neurological disorder might have on the reasoning on religion and spirituality, particularly regarding their theory of mind and interaction with metaphysical agents. The result contradicts several predictions about Asperger's syndrome and religion, and when analyzing to what extent the theory of mind was used when reasoning on intentionality, it seems as if the informants separate between different kinds of metaphysical agents. The question remains whether their reasoning on religion and spirituality is more influenced by having a specific cognitive style or by their cultural context.