hig.sePublications
Change search
Refine search result
1 - 1 of 1
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • harvard-cite-them-right
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • sv-SE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • de-DE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1.
    Pinedo, Cristina
    et al.
    Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Campus Universitario Río San Pedro, Puerto Real, Cádiz, Spain.
    Wright, Sandra A. I.
    University of Gävle, Faculty of Health and Occupational Studies, Department of Occupational and Public Health Sciences, Biology.
    Collado, Isidro G.
    Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Campus Universitario Río San Pedro, Puerto Real, Cádiz, Spain.
    Goss, Rebecca J. M.
    School of Chemistry, Biomedical Sciences Research Complex, University of St Andrews, Fife, Scotland.
    Castoria, Raffaello
    Dipartimento Agricoltura, Ambiente, Alimenti, Università degli Studi del Molise, Campobasso, Italy.
    Hrelia, Patrizia
    Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum-Università di Bologna, Bologna, Italy.
    Maffei, Francesca
    Dipartimento di Scienze per la Qualità della Vita, Alma Mater Studiorum-Università di Bologna, Campus Rimini, Rimini, Italy.
    Durán-Patrón, Rosa
    Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Campus Universitario Río San Pedro, Puerto Real, Cádiz, Spain.
    Isotopic Labeling Studies Reveal the Patulin Detoxification Pathway by the Biocontrol Yeast Rhodotorula kratochvilovae LS112018In: Journal of Natural Products, ISSN 0163-3864, E-ISSN 1520-6025, Vol. 81, no 12, p. 2692-2699Article in journal (Refereed)
    Abstract [en]

    Patulin (1) is a mycotoxin contaminant in fruit and vegetable products worldwide. Biocontrol agents, such as the yeast Rhodotorula kratochvilovae strain LS11, can reduce patulin (1) contamination in food. R. kratochvilovae LS11 converts patulin (1) into desoxypatulinic acid (DPA) (5), which is less cytotoxic than the mycotoxin (1) to in vitro human lymphocytes. In the present study, we report our investigations into the pathway of degradation of patulin (1) to DPA (5) by R. kratochvilovae. Isotopic labeling experiments revealed that 5 derives from patulin (1) through the hydrolysis of the γ-lactone ring and subsequent enzymatic modifications. The ability of patulin (1) and DPA (5) to cause genetic damage was also investigated by the cytokinesis-block micronucleus cytome assay on in vitro human lymphocytes. Patulin (1) was demonstrated to cause much higher chromosomal damage than DPA (5).

1 - 1 of 1
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • harvard-cite-them-right
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • sv-SE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • de-DE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf