Objective: The objective of this study was to describe the correlation between the fluid intake of hemodialysis patients and their self-assessed quality of sleep. Methods: A cross-sectional, correlational study, with explorative traits was performed as a quantitative multi-centre study. Data were analyzed for (n=180) patients. Interdialytic Weight Gain (IDWG) and a self-assessment of Pittsburgh Sleep Quality (PSQI) were used to estimate fluid intake and sleep quality. Results: There was no significant difference in fluid intake between male and female subjects. PSQI component scores for the entire study group (n=180) were poorest in Sleep Latency and Sleep Disturbance. When comparing PSQI components for male (n=116) and female (n=64) subjects, Use of Sleep Medications, global PSQI, Sleep Latency, and Daytime Dysfunction were significant, with poorest sleep quality for females. The correlation analysis between the PSQI components and IDWG (n=180) displayed significant correlations for Sleep Duration, Subjective Sleep Quality, and global PSQI. Conclusion: This study indicates there is a need for continued and improved fluid restriction compliance for both male and female hemodialysis patients. The appearent deficit in sleep quality in female patients compared to male patients needs to be further investigated in future studies.