The fashion business is dynamic and different from other businesses. Raw materials pass through various stages before shaping into the final products. These stages are design conceptualisation, raw material sourcing, manufacturing, distribution, and retailing. In the forward supply chain, products flow downstream, i.e., from manufacturing to the consumer. After end-of-use or end-of-life, the products move upstream for different reasons such as reuse, redesign, or recycling, hence closing the supply chain loop. Multiple facets of the reverse and closed-loop supply chain of the fashion business are discussed in this chapter, including factors affecting it. The most forward supply chain starts in the developing countries due to low wages. In contrast, the acquisition process of discarded products in reverse logistics starts in Western countries due to higher per capita income. Traditionally, charity organisations carried out reverse logistics activities of fashion products, however, many new players/companies are entering the reverse supply chain of the fashion business. The closed-loop supply chain of fashion is not much in practice though this is the need of today.