Background: Depression is a common psychological disorder. Pregnant women are susceptible to various influencing factors, and exposure to adverse factors may lead to mood disorders, resulting in postpartum depression. Without timely intervention and treatment, women’s health can be significantly compromised, and the infant’s health may also be affected.Aim: The aim of the study is to describe the influencing factors that affect the psychological problems of women with postpartum depressionDesign: A descriptive literature review that includes research using quantitative methods.Methods: This article is a descriptive literature review. The two authors selected quantitative research literature on factors influencing psychological issues in women with postpartum depression. After screening based on inclusion and exclusion criteria, 15 articles were compared and summarized for similarities and differences.Results: A total of 15 quantitative articles described the factors influencing psychological issues in women with postpartum depression, which were categorized into four groups: (1) physiological factors, (2) psychological factors, (3) social factors, and (4) familial factors.Conclusion: Postpartum women often struggled with role transitions and were susceptible to various influencing factors. Without timely intervention, irreversible damage to their physical and mental health could occur. Healthcare providers needed to enhance their professional competence to identify and mitigate high-risk factors, helping women with postpartum depression recover their health.